Mitochondria Membrane Integrity Antibodies

Target Information

Voltage-dependent anion channel (VDAC) proteins are abundant, pore-forming proteins belonging to the eukaryotic mitochondrial porins. It was discovered in the mitochondrial outer membrane. It also is expressed in the plasma membrane. At least three different VDAC genes have been identified in vertebrates. VDAC proteins are known to play an essential role in cellular metabolism and in the early stages of apoptosis. For example, VDAC contitutes a major pathway by which metabolites such as ADP/ATP, succinate and citrate are exchanged between the cytosol and mitochondria. And VDAC1 in the plasma membrane establishes a novel level of apoptosis regulation putatively via its redox activity.

Synonyms

16D10AD9AH5; 20B12AF2; 2610002H19Rik; 37BA11; 7H10BD4F9; AA408921; AL033343; AW457192; BR1-VDAC; brain-derived voltage-dependent anion channel 1; Complex III subunit 4; complex III subunit IV; CYC; Cyc1; cyclophilin 3; cyclophilin D; Cyclophilin F; Cycs; CYCSA; CYP3; CypD; CyP-D; CyP-F; CyP-M; cytc; Cytochrome b-c1 complex subunit 4; cytochrome c; Cytochrome C, expressed in somatic tissues; cytochrome c, somatic; cytochrome c1; Cytochrome c-1; cytochrome c1, heme protein, mitochondrial; E11AE12BD4; HCS; MC3DN6; MGC128356 protein; mitochondrial cyclophilin; mitochondrial Cyclophilin D; mVDAC1; mVDAC5; outer mitochondrial membrane protein porin 1; Peptidyl-prolyl cis-trans isomerase F, mitochondrial; peptidyl-prolyl cis-trans isomerase, mitochondrial; peptidylprolyl isomerase F; peptidylprolyl isomerase F (cyclophilin F); plasmalemmal porin; PORIN; Porin 31HL; porin 31HM; PPIase; PPIase F; PPIF; Rotamase F; rVDAC1; THC4; ubiquinol-cytochrome-c reductase complex cytochrome c1 subunit; Unknown (protein for MGC:134266); UQCR4; VDAC; Vdac1; VDAC-1; Vdac5; VDAC-5; voltage dependent anion channel 1; voltage-dependent anion channel 1; voltage-dependent anion-selective channel protein 1; Voltage-dependent anion-selective channel protein 5